Scientists reported the first successful birth of a baby from the transplanted womb of a dead donor. Progress can open the way for many more women with infertility problems.
For some women receiving uterus, transplantation is the only way to get pregnant. However, to date, receiving donations is limited to donations from volunteers.
Low numbers of donated organs slow down procedures
Donating uterus is a serious decision and complicated procedure. Up to now, only 39 transplants have been made worldwide, resulting in only 11 births since 2013.
Being able to use the uterus of deceased patients opens the possibility of more organs to be available but in the ten tests so far only this most recent birth has resulted in a successful birth.
Scientists from the University of São Paulo published the case study on the successful transplant and birth in the The Lancet newspaper.
Transplant donor born without womb
A native mother and donor was a 32-year-old woman who was born without a womb Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH).
The donated a 42-year-old woman who died of but.
Several months before the transplant, the recipient transferred an IVF procedure and had 8 fertilized oxygen eggs. The uterus transplant took 10.5 hours to complete.
A healthy baby girl born without complications
The recipient has shown no sign of an organic rejection and after five months has even undergone regular menstruation. Seven months after the intense surgery, the fertile eggs were implanted and healthy pregnancy continued.
The baby girl was born early at 35 weeks through a sealed section, the healthy baby was weighed 2.5 kg (5.5 lb). The donated womb was also removed during the Caesarean section.
Using dead donors open doors to more fertility treatment
In the months after birth, neither the baby nor her mother experienced some problems.
"The use of dead donations could extend the access to this treatment, and our results provide a demonstration concept for a new option for women with uterine infertility," says Dr. Dani Ejzenberg.
Dr. Ejzenberg, Hospitalo das Clínicas, Faculdade de Medicina da Universidade de São Paulo, led the investigation.
"The first generic transplants of live donors were a medical milestone, creating the possibility of childbirth for many sterile women with access to appropriate donors and the needed medical installations.
However, the need for a living gift is an important limitation, as donors are rare, usually being ready and eligible for family members or close friends.
The numbers of people ready and committed to donating organs on their own deaths are much larger than those of living donors, which offer a much more ample powerful donation. "
Doctors to continue researching
While the doctors who recreate the results, they warn that the procedure is still in its early stages and will require more research and cooperation before it becomes widely disseminated for sterile women.
Writing on Linkedin Dr. Antonio Pellicer, IVI-Rome, Italy notes;
"In general, the research carried out in this field (whether living or deceased) should maximize the live birth rate, minimize the risks for the patients involved in the procedures (donor, recipient and child born) and increase the availability of organs.
With the expansion of the field, the number of procedures will increase, and this will allow the community to set different types of study designs, such as comparative studies (ideally damaged) or long-term series.
In an expanding field as a transplanted uterus, the role of cooperative networks and societies such as the International Society of Upholstery Transplantation or new interest groups in existing scientific societies will be important. "