Wednesday , January 27 2021

Discover the area of ​​the hippocampus that determines social behavior

This small area that they called CA2 would be responsible for determining our social behaviors, as well as reproductive and eating behaviors. Wow!

It happened to everyone that someone does not like us just to see it. We may seem exaggerated or closed, but the truth is that this can explain what is more, what if I told you that the rest of the animals respond by acceptance or rejection before the meeting of other beings?


A group of researchers affirms that these reactions as well as a large part of our social behavior dominate a small part of the brain that they called CA2, according to a study recently published in the magazine Nature

This area is located within the hippocampus, a large brain structure that is related to the memory of human places, events and things. It even knew that CA2 was special in remembering encounter with others.

Discover a headache of a hip hop zone that determines social behaviors 1

CA2 is a small part difficult to study because of its position in the hippocampus. (Photo: Nature)

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What did they discover?

However, what is new is that the experiment, performed with mice, found that this area also serves as instinctive behaviors as social aggression. This means that this part of the brain chooses who is our friend and that our enemy is in a process where two variables enter into a game: social memory and instinct that can lead to violence.

According to Steven A. Siegelbaum, a professor and chair of the Department of Neurology at the Irving Medical Center at Columbia University, who has been the principal author of this research, this is a step to understand the behavior of the brain:

People and mice are social creatures. We both engage in learning and indigenous social interactions, which sometimes foster cooperation and, on the other hand, lead to competition for fellow officials, food and government. As the brain measures these conflicts, it was a confusing question.

Fit disorders?

Interestingly, it has been that the dysfunction of CA2 can be related to psychiatric diseases such as schizophrenia and bipolar disorders. Scientists explain that the fact that this area is involved in instinctive rejection and even violently can help find the responses to the behaviors of this type of patient.

The study in mice shows that the small area CA2, which is formed by a few thousand cells, acts as a link of social behaviors, allowing memory to influence the decision to participate in social aggression.

Although many other regions of the hippocampus are known, the small size of CA2 and its location makes this area a real challenge to study.

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Discover Ka2 Hippocampic zone that determines social behaviors 2

This experiment reveals important information about human behavior. (Photo: Very Interesting)

How were the mice: for the experiment, the researchers temporarily disable the CA2 by means of a mouse that lived alone in their cage, then introduced an intruder and observed their behavior. They found that when CA2 was deactivated, the tendency of resident mice to attack in comparison with their normal behavior significantly decreased. The different suggest that CA2 acts to promote aggressive behavior, as well as regulate social memory.

The whole experiment is very important because it reveals information on human behaviors and is intended to help in the understanding and subsequent treatment of changes to the same behavior:

People with schizophrenia show a wide range of behavior changes, including damaged social memory and changed levels of aggression. Could this be the result of loss or change in CA2 performance? And could these deficits be relieved by artificially increasing the activity of CA2? That is something that our research and that of others must reveal.

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