Preparatory tests of two medicines for bleeding ebola fever have shown great efficacy and, according to scientists, could save many lives. The US National Institute for Allergy and Infectious Diseases (NIAID), which was involved in the tests, reported Reuters.
The Ebola outbreak has plagued Congo, where more than 1800 people die in a year, according to the World Health Organization (WHO), a highly contagious virus is deadly in half the cases.
Four drugs have been tested in Congo and two have proven very effective. NIAID considers the results very good. The preparations will now be administered in Congo to all infected people.
– World Health Organization (WHO) August 12, 2019
Effective drugs known as Regnat-EB3 and mAb114 in the trials have shown that they are capable of neutralizing the effect of the virus on body cells. "These are the first drugs that have shown a significant reduction in mortality" in patients with Ebola in a scientific study, "said NIAID director Anthony Fauci.
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Both preparations were developed with the help of antibodies taken by people who survived Ebola. The other two drugs were excluded from the study because they proved ineffective.
Scientific trials began under the guidance of the WHO last November. Since then, 700 patients have received the experimental drug and the results are still in 499 of them. Of the REGNO-EB3 group, 29 percent of patients died, and 34 percent in the mAb114 group. For two discarded substances, mortality was 49 and 53 percent.
Survival rates in patients with low levels of virus in the blood were up to 94 percent with Regnat-EB3 and 89 percent with mAb114.
Sabu Mulangi, an infectious disease expert who participated in the study, said the result allows authorities to emphasize that with early treatment people have a 90% chance of survival.
Wellcome Trust director Jeremy Farrar said research has shown that tentative preparations can save lives and that the world is approaching at a time when Ebola will heal. "We will not release it, but we could be able to prevent national and regional epidemics," he said.
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